Less redness, less irritation, and fewer nights lying awake scratching.
Jessica M.
Nova, in real life.
Real Nova users. Real results.
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Customer, name withheld
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Daniella S.
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Olivia P.
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Sophie B.
What the studies found.
6 studies on cold plasma and eczema-prone skin, in plain English.
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Pilot trial · 22 people · 2021
Eczema scores and itch down in four weeks.
Three sessions over two weeks: treated eczema patches scored lower for severity and itch than sham-treated patches, with less S. aureus bacteria on the treated side.
Scientific ReportsStudy details
- Journal
- Scientific Reports, 2021
- Device
- MediPL Derm, an investigational microwave-driven argon plasma jet.
- Limits
- 22 people, four-week follow-up, severe eczema excluded.
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Review · 2023
A credible direction for eczema.
Summarises animal studies showing less dermatitis, less water loss and fewer S. aureus bacteria, plus one 22-person human pilot with lower eczema scores.
International Archives of Allergy and ImmunologyStudy details
- Journal
- International Archives of Allergy and Immunology, 2023
- Device
- kINPen MED, PlasmaDerm, MicroPlaSter and others discussed.
- Limits
- Mostly animal studies plus one small human pilot.
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Animal study · 2021
Lower dermatitis severity (animal study).
In mice with induced dermatitis, seven plasma applications over 17 days lowered severity, water loss and IgE.
Scientific ReportsStudy details
- Journal
- Scientific Reports, 2021
- Device
- RADIX-0502 argon plasma jet (MediPL).
- Limits
- Mice, not people; 17 days.
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Animal study · 2022
Calmer inflammation at the cellular level (animal study).
In mouse dermatitis, plasma reduced inflammatory signals and oxidative stress and raised a protective protein.
Frontiers in ImmunologyStudy details
- Journal
- Frontiers in Immunology, 2022
- Device
- Laboratory-built He/O₂ plasma jet.
- Limits
- Mice, not people; laboratory-built plasma source.
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Review · 2024
An emerging option for chronic itch.
Lists cold atmospheric plasma alongside phototherapy, laser and cryotherapy as an emerging device-based option for chronic itch.
Journal of the American Academy of DermatologyStudy details
- Journal
- Journal of the American Academy of Dermatology, 2024
- Device
- Multiple modalities.
- Limits
- A review of chronic itch in general, not eczema.
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Review · 2025
Most promising for inflamed skin.
A review of 12 human studies found cold plasma “appears to hold promise” for some conditions, with the stronger results in inflammatory skin conditions.
Journal of Integrative DermatologyStudy details
- Journal
- Journal of Integrative Dermatology, 2025
- Device
- Various clinic devices.
- Limits
- Twelve small studies; the authors call for larger trials.
The 60-Day Skin Trial.
Use Nova on your worst skin for 60 days. Opened, used, doesn’t matter — if your skin doesn’t change, send it back. Full refund, no restocking fee, no interrogation.
And a US$50 gift card for your time.
Air in. Plasma out. Nothing on the skin.
- 01The head charges the airA thin layer of air just above your skin becomes cold plasma: ionised air at skin temperature.
- 02It works at the surfaceNothing is applied and nothing is absorbed. No heat, no light, no ingredients.
- 03Minutes, then you’re done1–2 minutes per area, 3–5 times a week. No downtime, nothing to wash off.
Minutes. Not a routine.
- 01Clean, dry skinNothing on the skin first.
- 02Glide slowly1–2 minutes per area, light pressure.
- 033–5 times a weekThen your usual products, if you use any.
5–8 minutes a session. No gels, no cartridges, nothing to buy alongside it.
Same device. One difference.
- Standard plasma output
- The model most customers choose
- 3× the plasma output
- Same device, same size, same head
Trial, warranty and shipping are identical for both.
Technology, not another product.
Nova is used alongside prescribed care, not instead of it.
One price. Then nothing.
No refills, no cartridges, no subscription. Put your own number in.
- 1 year
- —
- 3 years
- —
- Nova, once
- $240.00
Everything you need. Nothing to re-buy.
- 1 × Nova device
- 1 × Charging cable
- 1 × Treatment head
- 1 × Fitted presentation case
- 1 × Quick-start guide
- 1 × Warranty card
- 1 × 60-Day Skin Trial card
No serums to repurchase. No refills. No subscription. The device is the routine.

The 60-Day Skin Trial.
Use Nova on your worst skin for 60 days. Opened, used, doesn’t matter — if your skin doesn’t change, send it back. Full refund, no restocking fee, no interrogation.
And a US$50 gift card for your time.
Before you decide.
Eczema
I’ve tried steroids, moisturisers, even Dupixent. Why would this be different?
Because it is not a cream, a steroid or a drug — nothing goes into your skin at all. It works at the surface, on the inflammation and the bacteria that keep a flare going. Keep whatever your clinician has prescribed; Nova runs alongside it, and you have 60 days to see what it does for you.
Will it irritate my skin or trigger a flare?
There is nothing in a session to irritate it: no heat, no ingredients, nothing absorbed. In the atopic dermatitis pilot, three sessions over two weeks were tolerated. Start on one small area, use your emollient afterwards, and if anything stings, stop and email us.
Is it suitable for children?
Nova is made for adults. For a child, ask their clinician first.
Using Nova
How do I use it?
Clean, dry skin. Glide the head slowly over each area with light pressure: 1–2 minutes per area, 5–8 minutes a session, 3–5 sessions a week. Then your usual products. Nothing to buy alongside it.
Does it hurt or burn?
No. Nova is non-thermal — the plasma runs at skin temperature. It is not a plasma pen. Some people feel a mild tingle during a session.
Can I keep using my skincare or prescription?
Yes. Nova first, on clean dry skin, then your usual products. Don’t stop a prescribed treatment without asking the clinician who prescribed it.
How do I look after it?
Keep the head clean and dry between sessions and charge it with the included cable. Anything else: email info@sub-zero.shop — a person replies within 1–2 business days.
Suitability & expectations
Who should check with a doctor first?
Nova is for adults. If you’re pregnant, have a pacemaker or implanted device, epilepsy, a skin-cancer history or an open wound, ask your clinician before using any cold-plasma device. Nova doesn’t diagnose anything and isn’t medical advice.
How long before I know if it’s working?
Think in weeks, not days. The published trials ran 4–12 weeks, which is why the trial is 60 days and not 14. Take a photo on day 0 in the same light — that is how you will see it.
Is there research, or just before-and-afters?
Both. The published research on cold plasma and skin is summarised in plain English further up this page, with the journal and the study details behind every card, and the before-and-afters are from customers using Nova at home.
Nova vs Nova Max
What’s the difference between Nova and Nova Max?
Same device, same technology, same head. Nova Max puts out three times the plasma power, so sessions are quicker and it suits larger or more stubborn areas. Trial, warranty and shipping are identical on both.
Buying, trial & payment
What if it isn’t right for me?
Email info@sub-zero.shop with your order number within 60 days of delivery. Opened and used is fine; send it back complete and the full purchase price goes back to your card, no restocking fee. You cover return postage. If your skin hasn’t changed, we also send a US$50 gift card to a retailer of your choice. The full refund policy is in the site footer.
What’s in the box?
Nova device, charging cable and treatment head in the fitted case, plus the quick-start guide, warranty card and 60-day trial card. No consumables, refills or cartridges, ever.
What does the lifetime warranty cover?
Manufacturing faults, for the life of the device, for the original buyer — we repair or replace it. Accidental damage, misuse and cosmetic wear aren’t covered.
Shipping and delivery?
Free worldwide, duties and customs covered. Dispatched in 1–2 business days; delivery 7–14 business days internationally, 3–7 within Australia. Tracking arrives by email.
How can I pay?
Card, Shop Pay and the wallets your device supports. One payment, no subscription. HSA/FSA cards work at checkout — Truemed handles the eligibility paperwork, and a refund under the trial goes back to the same card.
What real customers say.
27 reviews, eczema first.
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I’ve had eczema on and off since I was a teenager. The itching and flare-ups were the hardest part. Nova didn’t make it disappear overnight, but my skin became noticeably calmer and I wasn’t constantly reaching for creams throughout the day.
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My eczema would always flare up when I was stressed or the weather changed. Since using Nova, the patches on my arms and neck seem much less angry and irritated. The biggest difference is that my skin feels more stable overall.
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I’ve spent years cycling through moisturisers, steroid creams, and “eczema-safe” products. What surprised me about Nova was how well my skin tolerated it. Less redness, less irritation, and fewer nights lying awake scratching.
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The itching was honestly affecting my sleep more than the appearance of my eczema. After a few weeks with Nova, I noticed I wasn’t thinking about my skin nearly as much. The flare-ups still happen, but they don’t seem to escalate the same way they used to.
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I bought Nova hoping it would help calm the constant cycle of inflammation. My eczema hasn’t magically vanished, but my skin looks less reactive, feels less irritated, and recovers faster when I do have a flare-up. It’s become one of the few things in my routine that I genuinely don’t want to be without.
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I was so done with influencer skincare and was skeptical of anything new. The fact that it doesn’t use any ingredients is what actually made me try it. I’ve been using it for only 3 weeks and my skin hasn’t had a single angry flare-up and has acc improved. This is the first thing I’ve tried that didn’t make things worse and acc did something. So yeah, thumbs up from me.
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As a doctor I used to stress every night about which products to use and layer — toner, serum, creams. My skin still broke out lol. Nova removed all my second-guessing. I just use it and go straight to bed. It’s become the easiest and best part of my routine.
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I was buying $300 worth of skincare every two months and still breaking out (not a good look in my profession lmao). Now I use Nova daily and haven’t touched a single treatment cream in weeks. First time I feel like my skin is stable. Recommended it to all my clients aswell!!
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I’ve probably spent thousands on skincare. I’m not exaggerating. You name it, I’ve used it for sure. None of it ever really worked long term tho. Nova is the first thing that actually made my skin feel stable and made it consistently clear and smooth. After about 3 weeks, my breakouts and flare-ups have stopped and my redness went down massively. Love Nova, love Sub-Zero.
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I’ve actually stopped buying skincare. Nova is different. Within a few weeks of using Nova my breakouts stopped showing up randomly and my skin actually feels stable for the first time in years. I genuinely wish I found this sooner. COULD NOT RECOMMEND SOMETHING MORE!!!
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I’ve had rosacea for years (mainly flushing + background redness) and it used to stop me doing normal things like going out in the sun or even having a drink without my face flaring up. This hasn’t “cured” it, but my skin is way less reactive now. I can actually go out without constantly thinking about it. That’s been a big shift for me.
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Wasn’t expecting much at first, but after a couple weeks I noticed the redness on my cheeks wasn’t as intense. More importantly, I’m not getting those sudden flare-ups as often. I can work out again and not feel like my face is on fire after. Still early but definitely moving in the right direction.
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I’ve always had to be careful with everything — heat, skincare, even certain foods. Since using this, my skin feels a lot more stable. It’s not perfect, but I’m not constantly managing it anymore. I’ve been able to simplify my routine a lot and just live a bit more normally.
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Tried laser and a bunch of prescription stuff before this. Results were always mixed and sometimes made things worse. This feels a lot more controlled. My redness is still there but it doesn’t escalate like it used to. I can go out, be social, not stress about it constantly. For me that’s a big win.
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The red marks after my breakouts are finally fading instead of hanging around for months.
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I bought NOVA for acne, but the biggest surprise has been how much faster the leftover redness clears.
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My skin isn’t perfect, but the red patches from old pimples are so much less noticeable now.
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PIE has honestly bothered me more than the acne itself. After about six weeks, my cheeks look much more even in natural light.
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The difference in photos is what convinced me. Same lighting, same angle, way less redness.
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I still get the occasional spot, but it doesn’t leave that bright red mark for nearly as long.
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Foundation used to be the only thing that made my skin look even. I’m using a lot less now.
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I was expecting this to help active breakouts. Didn’t expect my old red marks to improve this much too.
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Very gradual, but definitely noticeable. My PIE looks softer every month.
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Those stubborn red marks on my cheeks have faded more in two months than they did in the six months before.
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My acne was mostly under control, but the red marks made it look like I was still breaking out constantly. NOVA has made a huge difference there.
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No dramatic overnight change. Just steadily less redness and a much more even-looking complexion.
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For me, the best result is that old breakouts actually look old now instead of staying bright red forever.


